Designed to be set-it and forget-it. You should not have to whitelist things.
In fact, I dare you to find and report any ;)
Ads, (Mobile) App Ads, Phishing, Malvertising, Malware, Spyware, Ransomware, CryptoJacking, Fraud, Scam
... Telemetry, Analytics, Tracking (Where not needed for proper functionality)
Torrent, Warez, Porn, Crypto Exchanges, News Satire, Slickdeals (or shopping sites in general), Google (shopping), Facebook, Twitter, Snapchat, Link Shortners, Affiliate/Tracking Links, etc.
It basically shouldn't interfere with anything you don't want it interfering with :)